The main cannabinoids are THC and cannabidiol (CBD). Research has found that the cannabis plant produces between 80 and 100 cannabinoids and about 300 non-cannabinoid chemicals. 1 The two main cannabinoids are delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). Cannabidiol (CBD), cannabidiolic acid (CBDA), cannabidiorcol (CBDC) Cannabidiol-C4 (CBDC), cannabidiol dimethyl ether (CBDD), cannabidiol monomethyl ether (CBDM), cannabidivarin (CBDV), cannabidivarinic acid (CBDVA) This list of cannabinoids contains the best known and most studied cannabinoids of these compounds.
Tetrahydrocannabinol (THC) is the best-known cannabinoid and is the chemical responsible for much of the psychoactive (psychotropic) and euphoric effects of cannabis, in addition to being used to treat serious illnesses such as PTSD and cancer. Cannabidiol (CBD), a generally non-psychoactive compound that has been shown to provide a wide range of medical benefits, such as pain relief, anxiety relief and depression relief, is another notable cannabinoid. Most people are familiar with tetrahydrocannabinol (THC) and cannabidiol (CBD). While THC and CBD are definitely important cannabinoids, there are many more worth exploring.
While the endocannabinoid system can use THC and CBD, it can also use MANY more cannabinoids. THC is the main psychoactive cannabinoid in marijuana and causes the high associated with cannabis use. The cannabis plant has two main subspecies, Cannabis indica and Cannabis sativa, and they can be differentiated by their different physical characteristics. The natural compounds in the cannabis plant are also known as phytocannabinoids, of which D-9-THC is the main psychoactive ingredient and have been extensively investigated in both animals and humans.
The main difference between the two cannabinoids is that THC has strong psychoactive effects, meaning that it causes a person to “get high”, while CBD is believed to have an antipsychoactive effect that controls or moderates the “high” caused by THC.