The main active component of the hemp plant Cannabis sativa is delta9-tetrahydrocannabinol (delta9-THC). In humans, psychoactive cannabinoids cause euphoria, improved sensory perception, tachycardia, antinociception, concentration difficulties and memory impairment. No matter how cannabis is consumed, it can cause immediate and long-term effects, such as changes in perception and increased heart rate. Over time, smoking cannabis can cause chronic coughing and other health problems.
Acute effects under the influence can sometimes include euphoria. Although some claim that cannabidiol (CBD), another cannabinoid found in cannabis in different amounts, can alleviate the adverse effects of THC experienced by some users, little is known about the effects of CBD on humans. Cannabinoid receptor antagonists have previously been successfully tested as antidotes for cannabis poisoning, reducing or eliminating the physiological and psychological effects of poisoning. Some of these products are currently under development as antidotes against cannabis.